Search results for "VERY LONG CHAIN POLYUNSATURATED FATTY ACIDS"

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Identification and quantification of phosphatidylcholines containing very-long-chain polyunsaturated fatty acid in bovine and human retina using liqu…

2010

The retina is one of the vertebrate tissues with the highest content in polyunsaturated fatty acids (PUFA). A large proportion of retinal phospholipids, especially those found in photoreceptor membranes, are dipolyunsaturated molecular species. Among them, dipolyunsaturated phosphatidylcholine (PC) molecular species are known to contain very-long-chain polyunsaturated fatty acids (VLC-PUFA) from the n-3 and n-6 series having 24-36 carbon atoms (C24-C36) and four to six double bonds. Recent interest in the role played by VLC-PUFA arose from the findings that a protein called elongation of very-long-chain fatty acids 4 (ELOVL4) is involved in their biosynthesis and that mutations in the ELOVL…

Spectrometry Mass Electrospray IonizationChimie analytiquePhospholipidChromosome DisordersTandem mass spectrometry01 natural sciencesBiochemistryHigh-performance liquid chromatographyRetinaAnalytical Chemistry03 medical and health scienceschemistry.chemical_compoundMacular Degeneration[CHIM.ANAL]Chemical Sciences/Analytical chemistryTandem Mass SpectrometryPhosphatidylcholineQUANTITATIVE ANALYSISAnimalsHumansOxazolesChromatography High Pressure Liquid030304 developmental biologychemistry.chemical_classificationPhosphatidylethanolamine0303 health sciencesVERY LONG CHAIN POLYUNSATURATED FATTY ACIDSChromatography010401 analytical chemistryOrganic ChemistryPHOSPHATIDYLCHOLINES;QUANTITATIVE ANALYSIS;LC-ESI-MS/MS;VERY LONG CHAIN POLYUNSATURATED FATTY ACIDS;RETINAGeneral MedicineLC-ESI-MS/MSeye diseases0104 chemical scienceschemistryBiochemistryDocosahexaenoic acidFatty Acids UnsaturatedPhosphatidylcholines[ CHIM.ANAL ] Chemical Sciences/Analytical chemistrylipids (amino acids peptides and proteins)CattleChromosomes Human Pair 6SphingomyelinPolyunsaturated fatty acidJournal of chromatography. A
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